Title:
抗炎症活性を有するα-アミノ酸誘導体
Document Type and Number:
Japanese Patent JP4769248
Kind Code:
B2
Abstract:
Compounds of the formula: are described in which Z, Q, X, L, m and n assume the meanings stated in the description. The compounds (I) inhibit the production of TNF alpha and may thus be useful in the treatment of inflammation and pathological conditions involving overproduction of said cytokine. They furthermore exhibit significant inhibitory activity on the proliferation of tumour cells and may thus be used for the treatment and/or prevention of tumorous, neurodegenerative or autoimmune disorders.
Inventors:
Massimo Pinoli
Rocco Mazza Ferro
Paolo Mascarni
Rocco Mazza Ferro
Paolo Mascarni
Application Number:
JP2007519757A
Publication Date:
September 07, 2011
Filing Date:
June 07, 2005
Export Citation:
Assignee:
ITALFARMACO SOCIETA PER AZIONI
International Classes:
C07C259/06; A61K31/166; A61K31/455; A61P25/00; A61P29/00; A61P35/00; A61P37/06; C07D213/80
Domestic Patent References:
| JP2000510472A | 2000-08-15 | |||
| JP2002513419A | 2002-05-08 | |||
| JP2004509941A | 2004-04-02 | |||
| JPH01146896A | 1989-06-08 |
Foreign References:
| WO2003070691A1 | 2003-08-28 | |||
| US4496540A | 1985-01-29 |
Attorney, Agent or Firm:
Yoshikazu Tani
Kazuo Abe
Kazuo Abe