Title:
AMINO ACID DERIVATIVES FUNCTIONALIZED ON N-TERMINAL CAPABLE OF FORMING DRUG INCAPSULATING MICROSPHERES
Document Type and Number:
Japanese Patent JP2023166457
Kind Code:
A
Abstract:
To provide amino acids, peptides, and polypeptide-lipids that are effective as a drug delivery system including the delivery of nucleotides to cells.SOLUTION: The present invention discloses compounds prepared by reacting terminal or internal amino groups with epoxides, acrylates, or aldehydes having lipophilic groups. For example, the following compound is illustrated.SELECTED DRAWING: None
Inventors:
DONG YIZHOU
KEVIN THOMAS LOVE
LANGER ROBERT S
DANIEL GRIFFITH ANDERSON
CHEN DELAI
CHEN YI
ARTURO JOSE VEGAS
AKINLEYE ALABI
ZHANG YUNLONG
KEVIN THOMAS LOVE
LANGER ROBERT S
DANIEL GRIFFITH ANDERSON
CHEN DELAI
CHEN YI
ARTURO JOSE VEGAS
AKINLEYE ALABI
ZHANG YUNLONG
Application Number:
JP2023137202A
Publication Date:
November 21, 2023
Filing Date:
August 25, 2023
Export Citation:
Assignee:
MASSACHUSETTS INST TECHNOLOGY
International Classes:
A61K47/54; A61K31/5377; A61K31/7088; A61K31/7105; A61K31/713; A61K38/00; A61K45/00; A61K47/24; A61K47/28; A61K47/42; A61K47/44; A61K47/69; A61K48/00; A61P1/16; A61P25/04; A61P25/28; A61P29/00; A61P35/00; A61P37/06; C07D207/16; C07D209/20; C07D233/64; C07D241/08; C07D265/32; C07D413/06; C07D487/04; C07D498/04; C07K5/08; C07K5/10; C07K5/12; C07K7/06; C07K7/08; C07K11/02; C07K14/00
Attorney, Agent or Firm:
Takuji Yamada
Yasushi Ochiai
Yasushi Ochiai
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