Title:
Amino pyrimidine kinase inhibitor
Document Type and Number:
Japanese Patent JP6215832
Kind Code:
B2
Abstract:
Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of CK1, CK1γ1, CK1γ2, CK1γ3, CK2, Pim 1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, the AKT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of CK1, CK1γ1, CK1γ2, CK1γ3, CK2, Pim 1, Pim2, Pim3, the TGFβ pathway, the Wnt pathway, the JAK/STAT pathway, the AKT pathway, and/or the mTOR pathway.
Inventors:
Bardino, Carmen M
Justin El, Caserta
Lee, Chi-Son
Dumas, Stephen A
Flanders, Yvonne El
Justin El, Caserta
Lee, Chi-Son
Dumas, Stephen A
Flanders, Yvonne El
Application Number:
JP2014539984A
Publication Date:
October 18, 2017
Filing Date:
October 24, 2012
Export Citation:
Assignee:
Jasco Pharmaceuticals, LLC
International Classes:
C07D417/14; C07D417/06; C07D487/04
Foreign References:
| WO2011079274A1 |
Attorney, Agent or Firm:
Yanagita Seiji