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Title:
アミノ-置換三環系誘導体および使用方法
Document Type and Number:
Japanese Patent JP2007523899
Kind Code:
A
Abstract:
Compounds of formula (I) wherein A and B are amine-substituted sidechains, Y 1 and Y 2 fonn various tricyclic cores, and R x is an optional substituent. Compounds and compositions of formula (I) are contemplated as well as methods for treating conditions or disorders prevented by or ameliorated by ±7 nAChR ligands that encompass compounds of formula (I) and other tricyclic derivatives. Methods of using amino-substituted derivatives also are described herein.

Inventors:
Michael Shulimp
Shitpee, kevin bii
Chi, Jiang Kuo
Lee, Tao
Pace, The Yenifar M
Clito A, Brittugu's
Bunnell, William H
Application Number:
JP2006552264A
Publication Date:
August 23, 2007
Filing Date:
February 04, 2005
Export Citation:
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Assignee:
ABBOTT LABORATORIES
International Classes:
C07C225/18; A61K31/137; A61K31/381; A61K31/397; A61K31/4025; A61K31/407; A61K31/4188; A61K31/439; A61K31/4545; A61K31/46; A61K31/496; A61K31/551; A61P3/10; A61P9/00; A61P9/10; A61P15/08; A61P17/02; A61P21/00; A61P25/04; A61P25/14; A61P25/18; A61P25/28; A61P29/00; A61P43/00; C07C211/25; C07C211/31; C07C217/24; C07C217/42; C07D205/04; C07D207/08; C07D207/12; C07D207/14; C07D209/88; C07D211/22; C07D211/46; C07D243/08; C07D295/10; C07D295/104; C07D307/91; C07D311/86; C07D333/76; C07D451/06; C07D453/02; C07D487/04; C07D487/08; C07D519/00
Domestic Patent References:
JP2005527472A2005-09-15
JP2004532899A2004-10-28
JP2004529936A2004-09-30
JP2000511528A2000-09-05
JPH10101591A1998-04-21
JPH06228095A1994-08-16
JPS52142077A1977-11-26
JPS4988852A1974-08-24
JPS4970975A1974-07-09
JPS558507B11980-03-04
Foreign References:
US4244954A1981-01-13
US4041165A1977-08-09
US3988335A1976-10-26
US3867531A1975-02-18
US3555043A1971-01-12
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura