Title:
AMINOBUTANOIC ACID DERIVATIVE
Document Type and Number:
Japanese Patent JP3470692
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide an aminobutanoic acid derivative inhibiting matrix metalloproteinase and useful for the prevention and/or treatment of rheumatism, arthrosteitis, pathologic bone resorption, osteoporosis, periodontosis, interstitial nephritis, arteriosclerosis, alveolar ectasia, hepatocirrhosis, corneus damage, metastatic invasion and proliferation of cancer cell, autoimmune disease (Crohn's disease, Sjoegren's disease, etc.), disease caused by the transmigration or infiltration of leukocyte cell through the vessel, vascularization, multiple sclerosis, aneurysm of aorta, endometriosis, etc.
SOLUTION: The objective aminobutanoic acid derivative and its salt are expressed by formula (I) (the definitions of the symbols in the formula are described in the specification).
Inventors:
Kanji Takahashi
Tsuneyuki Sugiura
Tsuneyuki Sugiura
Application Number:
JP2000322746A
Publication Date:
November 25, 2003
Filing Date:
September 07, 1998
Export Citation:
Assignee:
Ono Pharmaceutical Co., Ltd.
International Classes:
A61K31/16; A61K31/165; A61K31/166; A61K31/197; A61K31/277; A61K31/341; A61K31/343; A61K31/381; A61K31/385; A61K31/40; A61K31/403; A61K31/4035; A61K31/405; A61K31/415; A61K31/4164; A61K31/4166; A61K31/4178; A61K31/435; A61K31/44; A61K31/4406; A61K31/4409; A61K31/4418; C07D295/10; A61K31/4439; A61K31/445; A61K31/451; A61K31/454; A61K31/47; A61K31/495; A61K31/4965; A61K31/5375; A61P1/02; A61P1/16; A61P7/00; A61P9/00; A61P9/10; A61P11/00; A61P13/12; A61P15/00; A61P19/02; A61P19/10; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/00; A61P43/00; C07C233/63; C07C233/82; C07C235/16; C07C235/52; C07C237/06; C07C237/20; C07C259/06; C07C271/22; C07C311/21; C07C323/42; C07C323/59; C07C323/60; C07C327/30; C07D209/18; C07D209/24; C07D209/32; C07D209/48; C07D211/14; C07D211/46; C07D211/62; C07D211/70; C07D213/56; C07D213/61; C07D213/68; C07D213/79; C07D213/80; C07D215/14; C07D231/12; C07D233/64; C07D233/72; C07D295/12; C07D295/14; C07D295/16; C07D307/68; C07D307/80; C07D307/84; C07D333/16; C07D333/40; C07D333/60; C07D339/08; C07D401/12; C07D403/12; C07D405/12; C07F7/18; (IPC1-7): C07C235/52; A61K31/16; A61K31/166; A61K31/197; A61P1/02; A61P1/16; A61P7/00; A61P9/00; A61P9/10; A61P11/00; A61P13/12; A61P15/00; A61P19/02; A61P19/10; A61P27/02; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/00; A61P43/00; C07C259/06
Domestic Patent References:
| JP63165352A | ||||
| JP6210052A | ||||
| JP9505038A |
Other References:
【文献】国際公開89/02431(WO,A1)
【文献】米国特許2745875(US,A)
【文献】米国特許2745875(US,A)
Attorney, Agent or Firm:
Landlord Kunihisa
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