Title:
AMINOCYCLOPENTANONE AMIDES, MANUFACTURE AND DRUG COMPOSITION
Document Type and Number:
Japanese Patent JPS57102877
Kind Code:
A
Abstract:
Compounds are described of the formula (1) in which R1 is unsubstituted or substituted phenylalkyl, thienylalkyl or naphthylalkyl, or cinnamyl; R2 is a hydrogen atom, methyl or alkyl substituted by alkoxy or -COOH; W is alkylene; X is cis or trans -CH=CH- or -CH2CH2-; and Y is a saturated heterocyclic amino group having 5-8 ring members; and their salts and solvates. These compounds inhibit blood platelet aggregation and bronchoconstriction and may be formulated for use as antithrombotic and anti-asthmatic agents.
Inventors:
ERITSUKU UIRIAMU KORINTON
PIITAA HARETSUTO
KURISUTOFUAA JIYON UORISU
NOOMAN FURANKU HEIZU
PIITAA HARETSUTO
KURISUTOFUAA JIYON UORISU
NOOMAN FURANKU HEIZU
Application Number:
JP10343981A
Publication Date:
June 26, 1982
Filing Date:
July 03, 1981
Export Citation:
Assignee:
GLAXO GROUP LTD
International Classes:
A61K31/4433; A61K31/445; A61K31/535; A61K31/5375; A61K31/55; A61P7/02; A61P11/08; A61P43/00; C07C17/16; C07C29/147; C07C67/00; C07C401/00; C07C405/00; C07D267/10; C07D267/20; C07D295/116; C07D295/14; C07D295/155; C07D307/935; C07D309/12; C07D311/00; C07D333/12; C07D333/16; C07D333/22; C07D407/12; C07D409/12; C07D413/12; C07D413/14; (IPC1-7): A61K31/445; A61K31/495; A61K31/535; A61K31/54; A61K31/55; C07C177/00; C07D267/10; C07D295/14; C07D309/12; C07D311/00; C07D333/10; C07D407/12; C07D409/04; C07D409/12; C07D413/12; C07D413/14
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