Title:
アミノナフトキノン化合物、および疾患におけるユビキチン化−プロテアソーム系をブロックするための薬学的組成物
Document Type and Number:
Japanese Patent JP6820313
Kind Code:
B2
Abstract:
The invention relates to compounds of formula (I)with low cytotoxicity for blocking the ubiquitination-proteasome system in diseases. Accordingly, these compounds can be used in treatment of disorders including, but not limited to, cancers.
Inventors:
Yen, Yun
Riu, Jin-Pin
Bread, Shiou-Lin
Riu, Jin-Pin
Bread, Shiou-Lin
Application Number:
JP2018503202A
Publication Date:
January 27, 2021
Filing Date:
July 23, 2015
Export Citation:
Assignee:
Calgent Biotechnology Company, Limited
International Classes:
C07C237/38; A61K31/166; A61K31/167; A61K31/404; A61K31/415; A61K31/416; A61K31/4184; A61K31/426; A61K31/437; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/47; A61K31/495; A61K31/4965; A61K31/505; A61K31/519; A61K33/243; A61K45/00; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/14; A61P25/16; A61P25/28; A61P29/00; A61P31/00; A61P31/12; A61P35/00; A61P35/02; A61P37/02; A61P43/00; C07C237/40; C07D209/08; C07D213/75; C07D215/38; C07D215/40; C07D215/42; C07D231/38; C07D231/40; C07D231/56; C07D235/06; C07D235/30; C07D239/42; C07D241/20; C07D277/46; C07D295/135; C07D471/04; C07D487/04
Foreign References:
| US20110201609 | ||||
| WO2014074976A1 | ||||
| WO2006011136A2 | ||||
| KR1020130101908A | ||||
| US20040167189 |
Other References:
Bioorganic & Medicinal Chemistry,2010年,Vol.18, No.15,p.5576-5592
Bioorganic & Medicinal Chemistry Letters,2012年,Vol.22, No.8,p.2772-2774
Letters in Drug Design & Discovery,2013年,Vol.10, No.2,p.129-144
Cell Cycle,2009年,Vol.8, No.12,p.1940-1951
Pharmazie,1977年,Vol.32, No.5,p.269-270
Journal of Medicinal Chemistry,1969年,Vol.12, No.1,p.187-189
Bioorganic & Medicinal Chemistry Letters,2012年,Vol.22, No.8,p.2772-2774
Letters in Drug Design & Discovery,2013年,Vol.10, No.2,p.129-144
Cell Cycle,2009年,Vol.8, No.12,p.1940-1951
Pharmazie,1977年,Vol.32, No.5,p.269-270
Journal of Medicinal Chemistry,1969年,Vol.12, No.1,p.187-189
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto