Title:
アミノオキシ修飾オリゴヌクレオチド
Document Type and Number:
Japanese Patent JP4440346
Kind Code:
B2
Abstract:
Nucleotide compositions containing aminooxy moieties are provided. In accordance with preferred embodiments, oligonucleotides and oligonucleotide analogs are provided which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least one of the nucleoside moieties of the oligonucleotide is modified to include an aminooxy moiety.
Inventors:
Cook, Philip Dunn
Manoharan, Musier
Kawasaki, Andrew Mamoru
Manoharan, Musier
Kawasaki, Andrew Mamoru
Application Number:
JP53583898A
Publication Date:
March 24, 2010
Filing Date:
February 13, 1998
Export Citation:
Assignee:
Isis PharmaceuticalsInc
International Classes:
C07H19/06; A01N43/04; A61K31/7072; A61K31/7076; A61P43/00; C07H15/203; C07H19/04; C07H19/048; C07H19/16; C07H21/00; C07H21/02
Domestic Patent References:
| JP2088591A |
Other References:
Tetrahedron Letters, 1991年, Vol.32, No.51, p.7593-7596
Attorney, Agent or Firm:
Kazuo Shamoto
Shosuke Imai
Tadashi Masui
Tadahiko Kurita
Yasushi Kobayashi
Takashi Nakata
Shosuke Imai
Tadashi Masui
Tadahiko Kurita
Yasushi Kobayashi
Takashi Nakata