Title:
溶解性が増加した非晶質タクロリムス固体分散体及びこれを含む医薬組成物
Document Type and Number:
Japanese Patent JP4825223
Kind Code:
B2
Abstract:
An amorphous taclolimus solid dispersion comprising taclolimus, a substituted cyclodextrin derivative and an organic acid, which has a high thermodynamic stability and solubility, can provide an enhanced release rate and bioavailability.
Inventors:
Woo Jung Seo
Lee Hong Ki
Park Jung Hae
Lee Hong Ki
Park Jung Hae
Application Number:
JP2007554013A
Publication Date:
November 30, 2011
Filing Date:
February 03, 2006
Export Citation:
Assignee:
Hammi Farm. Seeo., LDT.
International Classes:
A61K31/706; A61K9/10; A61K47/12; A61K47/14; A61K47/20; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/40; A61P3/10; A61P11/08; A61P13/12; A61P17/14; A61P19/02; A61P27/02; A61P37/00
Domestic Patent References:
| JP2007504102A | 2007-03-01 | |||
| JP2007504103A | 2007-03-01 | |||
| JP2007527383A | 2007-09-27 |
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Kamahira Futami
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Kamahira Futami