Title:
ノルケタミンおよびケタミン/ノルケタミンプロドラッグの鎮痛的使用
Document Type and Number:
Japanese Patent JP2006510618
Kind Code:
A
Abstract:
The present invention relates to norketamine and ketamine/norketamine prodrugs, and methods of their use and analgesics. More particulary, the invention relates to norketamine and N-conjugated prodrugs of ketamine and norketamine, and methods of using these agents for the management of chronic pain without requiring administration of narcotics. The invention relates to self-management of pain on an outpatient basis comprising administering via conventional routes, including transdermal, nasal, rectal, oral, transmucosal, intravenous, intramuscular, and other routes, one or more doses of norketamine and/or ketamine/norketamine prodrugs effective to alleviate pain to a subject suffering from pain.
Inventors:
Crocs, Peter, A.
Rivera, Miguel
Rivera, Miguel
Application Number:
JP2004553852A
Publication Date:
March 30, 2006
Filing Date:
November 18, 2003
Export Citation:
Assignee:
Yaupon Therapeutics, Incorporated
International Classes:
C07D207/404; A61K9/08; A61K9/14; A61K31/135; A61K31/165; A61K31/166; A61K31/216; A61K31/222; A61K31/27; A61K31/357; A61K31/365; A61K31/4015; A61K31/4035; A61K47/10; A61K47/26; A61P25/04; A61P29/00; A61P43/00; C07C225/20; C07C235/46; C07C271/24; C07C323/62; C07D209/48; C07D307/88; C07D317/40
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ai Fujii
Ishii Teiji
Satoshi Fujita
Ai Fujii