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Title:
スルフェニル化合物、ラベル化試薬、及びペプチドの解析方法
Document Type and Number:
Japanese Patent JP3976048
Kind Code:
B2
Abstract:
A sulfenyl compound represented by the general formula: R-S-X (I)(wherein R represents an organic group having at least one constituent element labeled with an isotope, and X represents a leaving group); a labeling reagent comprising it; and a method of analyzing peptide using the labeling reagent. Preferably the organic group R comprises C, H, and N, and optionally O and/or P as the constituent element, and the isotope is a stable isotope selected from the group consisting of <2>H, <13>C, <15>N, <17>O, and <18>O.

Inventors:
Hiroki Kuyama
Hideharu Ando
Nishimura Nori
Application Number:
JP2004517238A
Publication Date:
September 12, 2007
Filing Date:
April 03, 2003
Export Citation:
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Assignee:
SHIMADZU CORPORATION
International Classes:
C07C313/16; C07C313/08; C07K2/00; G01N27/62; G01N33/15; G01N33/50; G01N33/68
Domestic Patent References:
JP8291134A
Foreign References:
WO2000011208A1
WO2001012594A1
Other References:
Journal of Organic Chemistry,1994年,59(12),p.3294-3400
Journal of Organic Chemistry,1991年,56(23),p.6638-6643
Bulletin of the Chemical Society of Japan,1986年,59(10),p.3291-3292
Chemische Berichte,1982年,115(12),p.3719-3736
Journal of Organic Chemistry,1979年,44(23),p.4135-4140
Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy,1995年,51A(14),p.2447-2451
Journal of Labelled Compounds and Radiopharmaceuticals,1983年,20(11),p.1243-1256
日本生化学会編,「タンパク質IV 構造機能相関」,東京化学同人,1991年,第57-58,64-66頁
Attorney, Agent or Firm:
Masahiro Okada