Title:
前立腺がん、脱毛症又は他の高アンドロゲン症候群の治療又は診断のためのアンドロゲン受容体サプレッサー
Document Type and Number:
Japanese Patent JP4806508
Kind Code:
B2
Abstract:
Substituted phenylalanines are provided comprising an hydantoin, urea or 2-hydroxyl, 2-methylpropionyl group, dimers thereof and alkyl, polyfluoroamido and haloarylamino derivatives thereof, as well as radiolabeled derivatives thereof. The compounds bind specifically to the androgen receptor and find use in indications associated with the androgen receptor, such as cell hyperplasia dependent on androgens, hirsutism, acne and androgenetic alopecia.
Inventors:
Sovac Milos
Seligson Allen
Douglas James Gordon The Third
Brown Jason W
Campion Brian
Seligson Allen
Douglas James Gordon The Third
Brown Jason W
Campion Brian
Application Number:
JP2001558407A
Publication Date:
November 02, 2011
Filing Date:
February 09, 2001
Export Citation:
Assignee:
Biophysical Inc.
International Classes:
C07C237/04; A61K31/165; C07D295/10; A61K31/167; A61K31/277; A61K31/40; A61K31/417; A61P5/00; A61P5/28; A61P17/10; A61P17/14; A61P35/00; C07C231/02; C07C237/22; C07C255/56; C07C255/60; C07C275/30; C07C317/46; C07C323/60; C07C335/08; C07C335/16; C07C335/22; C07D207/408; C07D233/02; C07D233/72; C07D233/86; C07D233/88; C07D207/40
Domestic Patent References:
| JP2000513362A | 2000-10-10 | |||
| JPH1029935A | 1998-02-03 | |||
| JPH10510845A | 1998-10-20 | |||
| JPH05194204A | 1993-08-03 |
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Hideto Takeuchi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Takaki Nishijima
Atsushi Hakoda
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Hideto Takeuchi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Takaki Nishijima
Atsushi Hakoda