Title:
動物病原体由来ポリペプチドおよびその遺伝子工学的利用
Document Type and Number:
Japanese Patent JP2021523733
Kind Code:
A
Abstract:
ゲノム編集および遺伝子調節を含む、遺伝子的およびエピゲノム的工学のためのポリペプチド、組成物およびそれらの使用方法を提供する。これらのポリペプチドおよび組成物は、対象の標的核酸に結合する核酸結合ドメインを含む。核酸結合ドメインは、レジオネラ目の細菌ならびにレジオネラおよびフランシセラ種のような動物病原体からのタンパク質において同定される反復単位に由来する反復単位を含む。
Inventors:
Urnov, Fodor
Stamatoyannopoulos, John A.
Funnel, Alistair Peedow
Stamatoyannopoulos, John A.
Funnel, Alistair Peedow
Application Number:
JP2021506378A
Publication Date:
September 09, 2021
Filing Date:
April 18, 2019
Export Citation:
Assignee:
Artius Institute for Biomedical Sciences
International Classes:
C12N15/31; A61K31/7088; A61K31/7105; A61K31/711; A61K35/76; A61K38/16; A61K48/00; A61P35/00; A61P43/00; C07K14/195; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/16; C12N15/86
Foreign References:
| WO2014018601A2 | 2014-01-30 |
Other References:
"DE SubName: Full=IcmE/DotG protein {ECO:0000313|EMBL:KTD51021.1}", DATABASE UNIPROT [ONLINE]，AC A0A0W0Y1V4, JPN6023012098, 28 March 2018 (2018-03-28), ISSN: 0005029299
"DE SubName: Full=Avirulence protein AvrBs3 {ECO:0000313|EMBL:KTD30443.1}", DATABASE UNIPROT [ONLINE]，AC A0A0W0WDL4, JPN6023012099, 28 March 2018 (2018-03-28), ISSN: 0005029300
"DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OGV28801.1}", DATABASE UNIPROT [ONLINE]，AC A0A1G0X562, JPN6023012100, 7 June 2017 (2017-06-07), ISSN: 0005029301
"DE SubName: Full=Avirulence protein AvrBs3 {ECO:0000313|EMBL:KTD30443.1}", DATABASE UNIPROT [ONLINE]，AC A0A0W0WDL4, JPN6023012099, 28 March 2018 (2018-03-28), ISSN: 0005029300
"DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OGV28801.1}", DATABASE UNIPROT [ONLINE]，AC A0A1G0X562, JPN6023012100, 7 June 2017 (2017-06-07), ISSN: 0005029301
Attorney, Agent or Firm:
Hidekazu Miyoshi
Masakazu Ito
Yuko Hara
Kazushi Ohbuchi
Masakazu Ito
Yuko Hara
Kazushi Ohbuchi