ANTHRACYCLINE SUBSTANCE, PREPARATION THEREOF AND BACTERIUM PRODUCING THE SAME

Title:

ANTHRACYCLINE SUBSTANCE, PREPARATION THEREOF AND BACTERIUM PRODUCING THE SAME

Document Type and Number:

Japanese Patent JPH03216198

Kind Code:

A

Abstract:

NEW MATERIAL:A compound of formula I (R1 is H, OH; R2 is H, lower alkyl; R3 is H, lower alkanoyl).

EXAMPLE: A compound of formula II.

USE: An antitumor agent.

PREPARATION: A microorganism belonging to the Nocardia strain such as Nocardia sp.-YL-01641P (FERM BP-2737) is cultured preferably at 25-32°C at a pH of 6-8 for 24-120 hours.

Inventors:

MORIOKA MIKIO
SASAKI TOSHIO
SUZUKI KENICHI
NAGAI KOJI
YAMAGUCHI YOJI
NOHARA CHIEKO
TOKUNAGA TATSUHIRO
HIRAMOTO MASASHI
TAKEBAYASHI YUKIHIRO

Application Number:

JP4651190A

Publication Date:

September 24, 1991

Filing Date:

February 27, 1990

Export Citation:

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Assignee:

YAMANOUCHI PHARMA CO LTD

International Classes:

C12P19/56; A61K31/70; A61K31/7028; A61K31/7034; A61K31/704; A61P25/30; C07H15/252; C12N1/20; C12R1/365; (IPC1-7): A61K31/71; C07H15/252; C12N1/20; C12P19/56

Attorney, Agent or Firm:

Shozo Nagai (1 person outside)

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