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Title:
抗PD−1/CD47二重特異性抗体及びその適用
Document Type and Number:
Japanese Patent JP6961090
Kind Code:
B2
Abstract:
The present invention provides a recombinant antibody. The recombinant antibody includes an anti-PD-1 antibody and human SIRPA extracellular domain. The N-terminus of the human SIRPA extracellular domain is linked to the C-terminus of the heavy chain of the anti-PD-1 antibody.

Inventors:
In Hwang
Famin Chan
Gun Sea
Application Number:
JP2020531011A
Publication Date:
November 05, 2021
Filing Date:
December 08, 2017
Export Citation:
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Assignee:
Hanks By Offer Matthewix, Incorporated
International Classes:
C12N15/13; A61K39/395; A61P35/00; C07K16/28; C07K19/00; C12N5/10; C12N15/62; C12N15/63; C12N15/861; C12N15/867; C12P21/08
Domestic Patent References:
JP2017525698A
JP2017510251A
JP2017510249A
Foreign References:
WO2017166804A1
Other References:
JCI Insight,2017年01月,Vol.2, No.1:e89140,p.1-15
Attorney, Agent or Firm:
Koichi Hirota
Yoshihiro Nagare
Naoko Matsuda