Title:
抗アテローム性動脈硬化症ジアリール化合物
Document Type and Number:
Japanese Patent JP3894949
Kind Code:
B2
Abstract:
The present invention is concerned with diaryl compounds of formula (I) and their use in medical therapy, particularly in the prophylaxis or treatment of a clinical condition for which an ACAT inhibitor is indicated, such as hyperlipidaema or atherosclerosis. The invention also relates to pharmaceutical compositions and processes for the preparation of compounds according to the invention.
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Inventors:
Arrow Smith, Richard James
Dan, Gordon
Karl Beetle, Franz Mann
Hodgson, Simon Teen By
Wortes, peter john
Dan, Gordon
Karl Beetle, Franz Mann
Hodgson, Simon Teen By
Wortes, peter john
Application Number:
JP50335795A
Publication Date:
March 22, 2007
Filing Date:
June 29, 1994
Export Citation:
Assignee:
THE WELLCOME FOUNDATION LIMITED
International Classes:
C07C233/25; A61K31/165; C07D295/18; A61K31/195; A61K31/215; A61K31/35; A61K31/351; A61K31/415; A61K31/445; A61K31/4465; A61K31/451; A61K31/535; A61K31/5375; A61P3/08; A61P9/10; A61P43/00; C07C231/12; C07C233/33; C07C233/54; C07C233/75; C07C235/06; C07C235/34; C07C235/54; C07C237/22; C07C237/24; C07C255/45; C07C255/46; C07C271/28; C07C275/36; C07C309/15; C07C311/21; C07C311/29; C07C317/22; C07C323/41; C07D211/32; C07D211/88; C07D233/60; C07D295/192; C07D309/04; C07D309/08; C07D309/10; C07D521/00
Domestic Patent References:
| JP50070345A | ||||
| JP2076842A | ||||
| JP56086141A | ||||
| JP60072787A |
Foreign References:
| WO1993011097A1 |
Other References:
BOWDEN,B.F. et al., Aust.J.Chem., 1975年,Vol.28, p.65-80
VICHKANOVA,S.A. et al., Farmakologiya i Toksikologiya, 1974年,Vol.37, No.6, p.711-715
VICHKANOVA,S.A. et al., Farmakologiya i Toksikologiya, 1974年,Vol.37, No.6, p.711-715
Attorney, Agent or Firm:
Kenji Yoshitake
Yukitaka Nakamura
Konno Akio
Noritaka Yokota
Yukitaka Nakamura
Konno Akio
Noritaka Yokota