NEW MATERIAL: A compound given by formula I [(m) is 0, or 1; W is H, alkyl, alkenyl, alkynyl, or Ph(CH2)n-(Ph is phenyl; (n) is 0-2), R1NHCO-(R1 is H, or alkyl), R2CONH-(R2 is H, or alkyl); X is formula II ((p) is 0-2), -CONH-, =CSNH or the like; Y is -(CH2)q ((q) is 1-3) or the like; Z is alkyl, but not N-[2-[(4- methylphenyl)methyl]phenyl]actamide or α-(p-tolyl)-o-cresolcarbanylate], their salts, solvates, or physiologically functional derivatives.
EXAMPLE: N-Heptyl-N'-(2,4-difluoro-6-[2-[4-(2.2-dimethylpropyl) phenyl]ethyl]phenyl urea.
USE: Agent for prevention or therapy of atherosclerosis.
PROCESS: A compound of formula III is reacted with a compound of formula IV (P of formula III and Q of formula IV are mutually reactive nucleophilic groups) to obtain a compound of formula I.
KURIFUOODO JIYON HARISU
RICHIYAADO JIEEMUSU AROUSUMISU
JIYON GOODON DAN
KEBIN JIYURIAN OKONAA
ROBAATO FUREDERITSUKU JIYOFURI
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