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Title:
経口投与用抗ガン性白金(IV)錯体
Document Type and Number:
Japanese Patent JP3648452
Kind Code:
B2
Abstract:
Platinum (IV) complexes for oral administration represented by the structural formula where A-A is a symmetrical diamine that can chelate to platinum and is selected from the group consisting of ethylene diamine, t(+/-)-1,2-diaminocyclohexane, 2,2-dimethyl-1,3-propanediamine, cyclohexane-1,1-dimethaneamine and tetrahydro-4H-pyran-4,4-dimethaneamine; and R is propionyl, butyryl or valeryl. These complexes are useful in the treatment of cancer.

Inventors:
Song, Yong So
Li, Sun Sil
Lee, Young-A
Kim, Kwan Mok
Lee, Jeong Ok
Application Number:
JP2000526469A
Publication Date:
May 18, 2005
Filing Date:
December 23, 1998
Export Citation:
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Assignee:
Korea Institute of Science and Technology
International Classes:
A61P35/00; C07C53/122; C07C53/124; C07C53/126; C07C209/00; C07C211/09; C07C211/10; C07C211/11; A61K31/28; C07C211/18; C07C211/36; C07D309/04; C07F13/00; C07F15/00; (IPC1-7): C07C211/09; C07C209/00; C07C211/10; C07C211/18; C07D309/04; C07F15/00
Foreign References:
US5288887
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda