線維症治療剤 - Kyorin Pharmaceutical Co., Ltd.

Title:

線維症治療剤

Document Type and Number:

Japanese Patent JP7204649

Kind Code:

B2

Abstract:

Disclosed is a phosphorylation inhibitor of SMAD2/3 protein or a therapeutic agent for fibrosis which contains as an active ingredient, a nucleic acid that suppresses NEK6 (NIMA-related serine/threonine kinase 6) gene expression.

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Inventors:

Kazuhisa Nakao
Junichi Ishiyama
Wataru Ichikawa
Atsushi Masui
Yunike Akasaka
Hidekazu Toyofuku
Aya Honda

Application Number:

JP2019532895A

Publication Date:

January 16, 2023

Filing Date:

July 30, 2018

Export Citation:

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Assignee:

Kyorin Pharmaceutical Co., Ltd.

International Classes:

A61K31/713; A61K31/7088; A61K47/54; A61K48/00; A61P43/00; C12N15/113

Foreign References:

US20040097441
WO2012017919A1

Other References:

BMB reports,2015年,Vol.48, No.8, pp.473-478
PloS one,2014年,Vol.9, No.4, e96095

Attorney, Agent or Firm:

Yoshiki Hasegawa
Yoshinori Shimizu
Katsusuke Kimoto
Sayaka Harada

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