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Title:
抗炎症剤
Document Type and Number:
Japanese Patent JP2008509974
Kind Code:
A
Abstract:
The invention provides compounds, compositions, and uses of compounds of general formula (I) or pharmaceutically acceptable salts thereof, for the preparation of a medicament intended to treat an inflammatory disorder wherein y is any integer from 1 to 8; z is any integer from 1 to 8; with the proviso that y and z cannot both equal 1; X is —C —(Y)k—(R1)n or SO2—(Y)k—(R1)n; k is 0 or 1; Y is a cycloalkyl or polycyloalkyl group (such as an adamantyl, adamantanemethyl, bicyclooctyl, cyclohexyl, cyclopropyl group); or Y is a cycloalkenyl or polycycloalkenyl group.

Inventors:
Granger, David John
Fox, david john
Application Number:
JP2007526560A
Publication Date:
April 03, 2008
Filing Date:
August 10, 2005
Export Citation:
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Assignee:
Cambridge Enterprise Limited
International Classes:
A61K31/439; A61K31/55; A61P9/14; A61P11/06; A61P17/02; A61P17/06; A61P19/10; A61P25/00; A61P25/28; A61P29/00; A61P31/12; A61P33/00; A61P35/00; A61P37/00; A61P37/06; A61P37/08; C07D451/14; C07D453/02; C07D487/08
Domestic Patent References:
JP5209471B22013-06-12
JP5248779B22013-07-31
JP5356687B22013-12-04
Foreign References:
WO1997017362A11997-05-15
Other References:
JPN6011039506; Bradley S. Davidson et al.: Tetrahedron Vol.49, No.30, 1993, p.6569-6574
JPN6011039507; David J. Fox et al.: Journal of Medicinal Chemistry Vol.45, No.2, 2002, p.360-370
JPN6012063615; 日本化学会編: 新実験化学講座14 有機化合物の合成と反応[III] , 1978, p.1391-1393
JPN6012063627; Eric F. V. Scriven and Kenneth Turnbull: Chemical Review Vol.88, No.2, 1988, p.297-368
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazumi Nakamura