Title:
ANTI-OBESITY POTENTIAL OF GARCINOL
Document Type and Number:
Japanese Patent JP2021185156
Kind Code:
A
Abstract:
To provide means for the therapeutic management of obesity, and means for the modification of gut microbiota.SOLUTION: Disclosed are compositions containing garcinol for the therapeutic management of obesity. More specifically, the invention relates to the use of garcinol for a) maintaining energy balance in mammalian adipose cellular systems, b) managing hypercholesterolemia and c) reducing weight gain in mammals. The modification of gut microbiota and the increase of beneficial microbe, Akkermansia muciniphila by garcinol are also disclosed.SELECTED DRAWING: Figure 1b
Inventors:
MUHAMMED MAJEED
KALYANAM NAGABHUSHANAM
LAKSHMI MUNDKUR
KALYANAM NAGABHUSHANAM
LAKSHMI MUNDKUR
Application Number:
JP2021130804A
Publication Date:
December 09, 2021
Filing Date:
August 10, 2021
Export Citation:
Assignee:
SAMI LABS LTD
International Classes:
A61K31/122; A23L33/105; A61K9/10; A61K9/107; A61K9/14; A61K9/20; A61K9/48; A61K9/68; A61P1/00; A61P1/04; A61P1/16; A61P3/04; A61P3/06; A61P9/00; A61P25/00; A61P29/00; A61P43/00
Domestic Patent References:
| JP2004506657A | 2004-03-04 |
Foreign References:
| US20120178801A1 | 2012-07-12 |
Other References:
PEI-SHENG LEE: "GARCINOL REDUCES OBESITY IN C57BL/6 MICE BY MODULATING THE COMPOSITION OF THE GUT MICROBIOTA", MEDICINAL & AROMATIC PLANTS, vol. VOL:6, NR:6, JPN5020007911, October 2017 (2017-10-01), pages 70, ISSN: 0005031525
SCIENTIFIC REPORTS, vol. 6, JPN6021008115, 2016, pages 33566, ISSN: 0004874886
FOOD AND FUNCTION, vol. 3, JPN6021008118, 2012, pages 49 - 57, ISSN: 0004874887
KEUN-YOUNG KIM: "GARCINIA CAMBOGIA EXTRACT AMELIORATES VISCERAL ADIPOSITY IN C57BL/6J MICE FED ON A HIGH-FAT DIET", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, vol. VOL:72, NR:7, JPN5020007908, 2008, pages 1772 - 1780, XP055562520, ISSN: 0004874888, DOI: 10.1271/bbb.80072
SCIENTIFIC REPORTS, vol. 6, JPN6021008115, 2016, pages 33566, ISSN: 0004874886
FOOD AND FUNCTION, vol. 3, JPN6021008118, 2012, pages 49 - 57, ISSN: 0004874887
KEUN-YOUNG KIM: "GARCINIA CAMBOGIA EXTRACT AMELIORATES VISCERAL ADIPOSITY IN C57BL/6J MICE FED ON A HIGH-FAT DIET", BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY, vol. VOL:72, NR:7, JPN5020007908, 2008, pages 1772 - 1780, XP055562520, ISSN: 0004874888, DOI: 10.1271/bbb.80072
Attorney, Agent or Firm:
Shinichiro Tanaka
▲吉▼田 和彦
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Takamitsu Hoshino
▲吉▼田 和彦
Hiroyuki Suda
Kazuo Yamazaki
Satsuki Ichikawa
Hironobu Hattori
Takamitsu Hoshino