ANTI-SIRP-α ANTIBODIES AND METHODS OF USE THEREOF

Title:

ANTI-SIRP-α ANTIBODIES AND METHODS OF USE THEREOF

Document Type and Number:

Japanese Patent JP2023022036

Kind Code:

A

Abstract:

To provide a pharmaceutical agent that down-regulates SIRP-α (anti-signal regulatory protein-α, SIRPA).SOLUTION: Provided is an isolated anti-signal regulatory protein α(SIRPA) antibody that selectively binds SIRPA and down-regulates SIRPA expressed on the cell surface.SELECTED DRAWING: Figure 3A

Inventors:

Pinsetic, Andrew
Rosenthal, Arnon
Lee, Sunju

Application Number:

JP2022176907A

Publication Date:

February 14, 2023

Filing Date:

November 04, 2022

Export Citation:

Click for automatic bibliography generation Help

Assignee:

Alexandr Elsie

International Classes:

C12N15/13; A61K39/395; A61P25/14; A61P25/16; A61P25/28; A61P29/00; A61P31/00; A61P35/00; A61P35/02; A61P37/06; A61P43/00; C07K16/28; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63; C12P21/02; C12P21/08

Attorney, Agent or Firm:

Sonoda & Kobayashi Patent Attorneys Corporation

Previous Patent: JPWO2023022035

Next Patent: Natural killer cells and uses thereof