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Title:
ANTIBIOTIC SUBSTANCE, ITS PREPARATION, AND MICROORGANISM
Document Type and Number:
Japanese Patent JPS6147491
Kind Code:
A
Abstract:

NEW MATERIAL:The compound of formula I (R1 is H or formylamino; R2 is 1W 2 amino acid or peptide residue selected from serine and alanine, or H; R3 is group of formula II or -CH2-NH2) and its salt, having the following physical and chemical properties. White powder (dihydrochloride of the compound of formula I wherein R1 is -NH- CHO, R2 is H and R3 is group of formula II); molecular weight, (M+H)+ 704 by SIMS process; molecular formula, C26H41N9O12S.2HCl. (2H2O); elemental analysis (%), C 38.43, H 5.83, N 15.51, O 27.56, S 3.95, Cl 8.73; solubility, easily soluble in water, hydrated acetone and hydrated alcohol, hardly soluble in dimethyl sulfoxide, methanol, acetone and ethyl acetate.

USE: Antibacterial agent.

PREPARATION: The compound of formula I can be produced and accumulated by culturing Xanthomonas lactamgena YK-280 (FERM 7602) in a proper medium under the optimum conditions, i.e. at 17W24°C and 6W7 pH for 24W144hr.


Inventors:
HARADA SETSUO
NOZAKI YUKIMASA
ONO HIDEO
Application Number:
JP16869184A
Publication Date:
March 07, 1986
Filing Date:
August 10, 1984
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
International Classes:
C07D501/28; A61K31/545; A61K31/546; A61P31/04; C07D501/57; C12P35/00; C12P35/06; C12P35/08; C12R1/64; (IPC1-7): A61K31/545; C07D501/28; C07D501/57; C12P35/00; C12P35/08; C12R1/64
Attorney, Agent or Firm:
Hiroshi Iwata