NEW MATERIAL:A compound shown by the formula. Exhibiting the following physical and chemical properties. White crystal. Melting point: 164.5W168°C; [α]D25=-6.6 (C=2, methanol). Elemental analysis %: C 63.03, H 8.80, and N 1.84. Molecular weight: 725. (resulting from electron impact mass spectrum). Molecular formula: C38H63NO12. Soluble in lower alcohol, ester, ketone, benzene, weakly acidic water, insoluble in weakly alkali water, petroleum ether, n-hexane, etc. Positive in molish, anthrone, conc. sulfuric acid reaction, and negative in biuret, ninhydrin reaction, etc.
USE: An antibacterial agent against Gram-positive and Gram-negative bacteria, mycoplasma, etc.
PROCESS: For example, a bacterium, e.g., Stretomyces fradiae YT-3927(FERM- P5758), is cultivated preferably under aerobic conditions, at 25W35°C in a pH of approximately neutrality of 6W8 for 2W12 days.
| WO/2002/014482 | POLYKETIDES AND THEIR SYNTHESIS |
| JP2006296430 | NATAMYCIN RECOVERY |
YAMAMOTO MASAO
TAKADA KAZUAKI
KIYOSHIMA KOUKI
ISHIKURA TOMOYUKI
TAKEUCHI TOMIO
UMEZAWA HAMAO
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