Title:
抗生物質トリプロペプチン類およびその製造法
Document Type and Number:
Japanese Patent JP4054576
Kind Code:
B2
Abstract:
By culturing Lysobacter sp. BMK333-48F3 (deposit number of FERM BP-7477), an antibiotic, tripropeptin Z, tripropeptin A, tripropeptin B, tripropeptin C or tripropeptin D represented by the general formula (I): wherein R is 7-methyl-octyl group, 8-methyl-nonyl group, 9-methyl-dodecyl group, 10-methyl-undecyl group or 11-methyl-dodecyl group, is obtained as antibiotics having excellent antibacterial activities against bacteria and having a novel molecular structure. These tripropeptins each have an excellent antibacterial activity against various bacteria and drug-resistant strains thereof, such as methicillin-resistant strains and vancomycin-resistant strains.
Inventors:
Tomio Takeuchi
Hideki Hashizume
Masayuki Igarashi
Hiroshi Naganawa
Hamada Masaru
Hideki Hashizume
Masayuki Igarashi
Hiroshi Naganawa
Hamada Masaru
Application Number:
JP2001572539A
Publication Date:
February 27, 2008
Filing Date:
March 28, 2001
Export Citation:
Assignee:
Foundation for Microbial Chemistry
International Classes:
C07K7/06; A61K38/00; A61P31/04; C07K11/02; C12N1/20; C12P21/04
Foreign References:
| US4754018 |
Attorney, Agent or Firm:
Takao Hamano
Morita Tetsuji
Morita Tetsuji