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Title:
ヒトCTLA-4に対する抗体
Document Type and Number:
Japanese Patent JP7214623
Kind Code:
B2
Abstract:
The invention relates to new anti-hCTLA-4 antibodies that bind to a different epitope than prior art anti-CTLA4 antibodies, methods to produce these antibodies and therapeutic and diagnostic uses of these antibodies. These antibodies show a similar affinity for the CTLA4 antigen and they are also able to block the binding of CTLA4 to CD80 and/or CD86.

Inventors:
Han Ehnennam, Hans
Juan Elsus, Andrea
Crates, yost
Hülsik, Durfit Luce
Fink, Paul
Application Number:
JP2019505381A
Publication Date:
January 30, 2023
Filing Date:
August 01, 2017
Export Citation:
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Assignee:
SAIROPA B.V.
International Classes:
C12N15/13; A61K39/395; A61P35/00; A61P35/02; A61P37/04; A61P43/00; C07K16/28; C07K16/46; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/62; C12N15/63
Domestic Patent References:
JP2002537226A
JP2003520828A
Attorney, Agent or Firm:
Patent Attorney Fukami Patent Office