Title:
ANTIBODIES AGAINST T CELL, IMMUNOGLOBULIN DOMAIN AND MUCIN DOMAIN 1 (TIM-1) ANTIGEN AND USES THEREOF
Document Type and Number:
Japanese Patent JP2014144971
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide antibodies binding to the antigen TIM-1 and uses of the antibodies.SOLUTION: There are provided fully human monoclonal antibodies binding to the antigen TIM-1. Isolated polynucleotide sequences encoding, and amino acid sequences comprising, heavy and light chain immunoglobulin molecules, and particularly provided are sequences corresponding to contiguous heavy and light chain sequences spanning the framework regions (FR's) and/or complementarity determining regions (CDR's), specifically from FR1 through FR4 or CDR1 through CDR3.
Inventors:
LANDES GREGORY M
CHEN FRANCINE
BEZABEH BINYAM
FOLTZ IAN
CHEN FRANCINE
BEZABEH BINYAM
FOLTZ IAN
Application Number:
JP2014082974A
Publication Date:
August 14, 2014
Filing Date:
April 14, 2014
Export Citation:
Assignee:
ABGENIX INC
International Classes:
C07K16/28; A61K39/395; A61K51/00; A61P13/12; A61P35/00; C07K16/46; C12N5/06; G01N33/53; C07K16/42; C12N15/09; C12P21/08
Domestic Patent References:
| JP2001505761A | 2001-05-08 |
Foreign References:
| WO2002098920A1 | 2002-12-12 | |||
| WO2003002722A2 | 2003-01-09 | |||
| WO2002098920A1 | 2002-12-12 |
Other References:
JPN6016017477; ＴＨＥ ＪＯＵＲＮＡＬ ＯＦ ＢＩＯＬＯＧＩＣＡＬ ＣＨＥＭＩＳＴＲＹ Ｖｏｌ． ２７７， Ｎｏ． ４２, 2002, ｐｐ．３９７３９-３９７４８
Attorney, Agent or Firm:
Mitsuo Tanaka
Yamasaki 宏
Norifumi Tomita
Manami Sasakura
Yamasaki 宏
Norifumi Tomita
Manami Sasakura