緑膿菌の血清型I型リポ多糖に対する抗体

Title:

緑膿菌の血清型I型リポ多糖に対する抗体

Document Type and Number:

Japanese Patent JP2013520160

Kind Code:

A

Abstract:

Provided is a novel antibody having an excellent antibacterial activity against P. aeruginosa. By using plasmablasts obtained from cystic fibrosis patients with chronic P. aeruginosa pulmonary infection as starting materials, antibodies which bind to LPS of a P. aeruginosa strain of serotype G and which have excellent antibacterial activities in vitro and in vivo were successfully obtained.

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Inventors:

Jiro Tanaka
Peter Sia Andersen
Takafumi Okutomi
Inaba Tsuneyoshi
Keiko Otsuka
Hirotomo Akabane
Hoshi Name Yukari
Hiroshi Nagasono
Masashi Kumagai

Application Number:

JP2012538103A

Publication Date:

June 06, 2013

Filing Date:

February 18, 2011

Export Citation:

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Assignee:

meiji seika Pharma Co., Ltd.

International Classes:

C12N15/09; A61K39/395; A61P11/00; A61P31/04; C07K16/12; C12N5/10; G01N33/569

Attorney, Agent or Firm:

Patent Business Corporation St. Crest International Patent Office

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