Title:
24P4C12タンパク質に結合する抗体薬物結合体(ADC)
Document Type and Number:
Japanese Patent JP2012519711
Kind Code:
A
Abstract:
Antibody drug conjugates (ADC's) that bind to 24P4C12 protein and variants thereof are described herein. 24P4C12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
Inventors:
Gudas Gene
Jakobo Bits Aya
Anjiri
Morrison Robert Kendall
Morris Karen Jane Meyrick
Chia Xiao
Benjamin Dennis
Maser loose
Center peter
Jakobo Bits Aya
Anjiri
Morrison Robert Kendall
Morris Karen Jane Meyrick
Chia Xiao
Benjamin Dennis
Maser loose
Center peter
Application Number:
JP2011553153A
Publication Date:
August 30, 2012
Filing Date:
March 05, 2010
Export Citation:
Assignee:
Agensis, Inc.
Seattle Genetics, Inc.
Seattle Genetics, Inc.
International Classes:
A61K38/00; A61K47/42; A61K47/48; A61P35/00; C07K16/30; C12N15/02
Domestic Patent References:
| JP2010537671A | 2010-12-09 | |||
| JP2006508163A | 2006-03-09 | |||
| JP2008546792A | 2008-12-25 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto