Title:
ANTICANCER AGENT
Document Type and Number:
Japanese Patent JPH0687736
Kind Code:
A
Abstract:
PURPOSE: To obtain an anticancer agent containing 1-methoxy-2formyl-3- hydroxyanthraquinone obtained from extract of Morinda citrifolia which is a tropical plant as an active ingredient.
CONSTITUTION: Morinda citrifolia naturally grown or partially cultured in Southeast Asia is extracted with a solvent such as chloroform at ambient temperature to 60°C to afford 1-methoxy-2-formyl-3-hydroxyanthraquinone of the formula. Using this compound as an active ingredient, the objective anticancer agent is provided. This active ingredient exhibits action capable of inhibiting action of ras cancer gene product. Namely, this active ingredient exhibits activity capable of inhibiting proliferation of cancer cell and normalizing the form of the cell.
Inventors:
UMEZAWA KAZUO
IMOTO MASAYA
OBA SHIGERU
KOYANO TAKASHI
KOMIYAMA YOSHIKO
IMOTO MASAYA
OBA SHIGERU
KOYANO TAKASHI
KOMIYAMA YOSHIKO
Application Number:
JP26431192A
Publication Date:
March 29, 1994
Filing Date:
September 07, 1992
Export Citation:
Assignee:
UMEZAWA KAZUO
TONEN CORP
TONEN CORP
International Classes:
A61K31/12; A61K31/122; A61K36/18; A61P35/00; (IPC1-7): A61K31/12
Attorney, Agent or Firm:
Kohei Kubota (3 outside)
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