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Title:
高リスク群ヒトパピローマウイルスの中和抗体を誘導する抗原
Document Type and Number:
Japanese Patent JP4825958
Kind Code:
B2
Abstract:
[PROBLEMS] To provide an antigen which can be used against at least a high risk-type human papillomavirus (HPV) and which is a vaccine antigen having a higher type-commonality. [MEANS FOR SOLVING PROBLEMS] A capsid comprising an assembly of a chimeric protein having at least one L2 epitope selected from human papillomavirus L2 epitopes inserted to the loop site in human papillomavirus type 16 L1 protein; a chimeric protein having at least one L2 epitope selected from human papillomavirus L2 epitopes inserted to the loop site in human papillomavirus type 16 L1 protein; and a process for producing a capsid comprising an assembly of the chimeric protein, the process comprising assembling the chimeric protein to form the capsid.

Inventors:
Tadahito Kanda
Kazunari Kondo
Application Number:
JP2005232233A
Publication Date:
November 30, 2011
Filing Date:
August 10, 2005
Export Citation:
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Assignee:
Human Science Promotion Foundation
International Classes:
C07K14/025; C07K19/00; C12N15/09; C12P21/02; A61K39/12; A61P15/00; A61P31/20; A61P35/00
Other References:
J Virol, vol.77, p.8386-8393 (2003)
Virology, vol.245, p.353-359 (1998)
Virology, vol.309, p.32-40 (2003)
J Gen Virol, vol.76, p.1141-1153 (1995)
ウイルスを標的とする発がん予防の研究 平成17年度 総括・分担研究報告書、2006年、第6-8頁
ウイルスを標的とする発がん予防の研究 平成17年度合 総括・分担研究報告書、2006年、第1-5頁
Attorney, Agent or Firm:
Patent Service Corporation Patent Office Sykes



 
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