Title:
水痘・帯状疱疹ウイルスの抗原バリアントおよびその使用
Document Type and Number:
Japanese Patent JP7247226
Kind Code:
B2
Abstract:
The present invention relates to an antigen variant and a use thereof, the antigen variant being a protein, among surface proteins (gE) of the varicella zoster virus, exhibiting a high expression level and high immunogenicity, and thus, when the antigen variant is used as a vaccine composition, the vaccine composition has more excellent safety compared to a live virus vaccine, and the antigen variant exhibits a higher expression level in a host cell compared to other antigens, and thus is useful as a vaccine for preventing or treating chicken pox or herpes zoster caused by the varicella zoster virus.
Inventors:
Nam Hyo Jung
Ji Gayoung
Kim Eun Mi
Ji Gayoung
Kim Eun Mi
Application Number:
JP2020565344A
Publication Date:
March 28, 2023
Filing Date:
May 22, 2019
Export Citation:
Assignee:
MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
International Classes:
C12N15/38; A61K39/25; A61P31/22; C07K14/04; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63
Domestic Patent References:
| JP2008531637A | ||||
| JP2014508522A |
Foreign References:
| CN102517302A | ||||
| WO2006128026A2 | ||||
| WO2017090744A1 | ||||
| WO2016096968A1 |
Attorney, Agent or Firm:
Yamato Kento
Michiko Matsutani
Yoko Sakurai
Keiji Sakata
Michiko Matsutani
Yoko Sakurai
Keiji Sakata
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