Title:
ANTIHYPERTENSIVE AMIDES
Document Type and Number:
Japanese Patent JPS5618953
Kind Code:
A
Abstract:
Compounds of the structure: wherein R1, R2, R3, R4, R5, and R6 are hydrogen, alkyl, alkenyl, alkynyl, phenyl-alkyl, or cycloalkyl, n is an integer from 0 to 4 inclusive, M is alkenyl, alkynyl, cycloalkyl, cycloalkyl-alkyl, polycycloalkyl, polycyclo-alkyl-alkyl, aryl, aralkyl, heteroaryl, heteroaryl-alkyl, hetero-cycloalkyl, hetero-cycloalkyl-alkyl, alkoxyalkyl, alkylthioalkyl, alkylamino-alkyl, dialkylamino-alkyl, fused aryl-cycloalkyl, fused aryl-cycloalkyl-alkyl, fused heteroaryl-cycloalkyl, or fused heteroaryl-cycloalkyl-alkyl, Y is hydroxy, alkoxy, amino, or substituted amino, aminoalkanoyl, aryloxy, aminoalkoxy, or hydroxyalkoxy, and R7 is hydrogen, alkanoyl, carboxylalkanoyl, hydroxyalkanoyl, amino-alkanoyl, cyano, amidino, carbalkoxy, ZS, or wherein Z is hydrogen, alkyl, hyroxyalkyl, aminoalkyl or the radical wherein R1, R2, R3, R4, R5, R6, n, M and Y are as described above; and where Y is hydroxy their non-toxic, pharmaceutically acceptable alkali metal, alkaline earth metal, and amine salts.
Inventors:
JIYON TEI SUU
JIERII DABURIYUU SUKAIRESU
ARUFURETSUDO SHIYUWABU
BURUUSU II UIRIAMUZU
JIERII DABURIYUU SUKAIRESU
ARUFURETSUDO SHIYUWABU
BURUUSU II UIRIAMUZU
Application Number:
JP9515980A
Publication Date:
February 23, 1981
Filing Date:
July 14, 1980
Export Citation:
Assignee:
USV PHARMA CORP
International Classes:
A61K31/165; A61K31/19; A61K31/195; A61K31/21; A61K31/215; A61K31/22; A61P9/00; A61P9/12; A61P43/00; C07C67/00; C07C313/00; C07C323/60; C07C325/00; C07C327/20; C07C327/22; C07C327/32; C07C329/14; A61K31/16; C07C329/16; C07C335/32; C07D207/08; C07D211/26; C07D213/38; C07D213/40; C07D213/75; C07D215/38; C07D217/22; C07D219/14; C07D235/30; C07D239/42; C07D277/46; C07D307/22; C07D307/52; C07D307/66; C07D307/82; C07D309/14; C07D317/66; C07D319/18; C07D333/20; C07D333/36; C07D333/48; (IPC1-7): A61K31/16; A61K31/19; A61K31/21; C07C149/23; C07C149/41; C07C153/05; C07C154/00; C07C157/14; C07C161/00; C07D207/08; C07D213/74; C07D215/38; C07D235/30; C07D239/42; C07D307/22; C07D307/66; C07D333/36
Domestic Patent References:
| JPS5291823A | 1977-08-02 | |||
| JPS52136117A | 1977-11-14 | |||
| JPS5371014A | 1978-06-24 | |||
| JPS5371015A | 1978-06-24 | |||
| JPS53112810A | 1978-10-02 | |||
| JPS5463017A | 1979-05-21 |
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