Title:
抗酸化炎症モジュレーター:C環中に飽和を有するオレアノール酸誘導体
Document Type and Number:
Japanese Patent JP5529850
Kind Code:
B2
Abstract:
This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
More Like This:
| JP3441488 | NEW SAPONIN COMPOUND AND DESACYL SAPONIN COMPOUND |
| JP2012144574 | MEDICINAL COMPOSITION AND METHOD OF USE |
| JP2010018552 | RENIN INHIBITOR CONTAINING SOYASAPONIN I |
Inventors:
Anderson Eric
Jang Shin
Ryu Shaofen
Bisnick melane
Jang Shin
Ryu Shaofen
Bisnick melane
Application Number:
JP2011505258A
Publication Date:
June 25, 2014
Filing Date:
April 20, 2009
Export Citation:
Assignee:
Riata Pharmaceuticals, Inc.
International Classes:
C07J63/00; A61K31/56; A61P1/00; A61P3/00; A61P3/04; A61P3/10; A61P9/00; A61P9/10; A61P9/12; A61P13/12; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P35/00; A61P35/02; C07J71/00
Domestic Patent References:
| JP2006347952A | ||||
| JP2006515859A | ||||
| JP2002530272A | ||||
| JP2001240573A |
Foreign References:
| CN101117348A |
Other References:
HONDA,T. et al,Design and synthesis of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, a novel and highly active inhi,Bioorganic & Medicinal Chemistry Letters,1998年,Vol.8, No.19,p.2711-2714
Botanical Studies,2006年,47,339-368
Tetrahedron,1962年,18,827-838
Bulletin of the Chemical Society of Japan,1978年,51(3),884-888
HONDA,T. et al,Synthetic Oleanane and Ursane Triterpenoids with Modified Rings A and C: A Series of Highly Active I,Journal of Medicinal Chemistry,2000年,Vol.43, No.22,p.4233-4246
Botanical Studies,2006年,47,339-368
Tetrahedron,1962年,18,827-838
Bulletin of the Chemical Society of Japan,1978年,51(3),884-888
HONDA,T. et al,Synthetic Oleanane and Ursane Triterpenoids with Modified Rings A and C: A Series of Highly Active I,Journal of Medicinal Chemistry,2000年,Vol.43, No.22,p.4233-4246
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto