Title:
ANTIRHEUMATIC MEDICINE
Document Type and Number:
Japanese Patent JP3184923
Kind Code:
B2
Abstract:
PURPOSE: To obtain an antirheumatic medicine containing lactoferrin as an active ingredient and having a lactoferrin-inhibiting activity.
CONSTITUTION: This antirheumatic medicine contains as an inactive ingredient lactoferrin which is a protein contained in the milks and tear solutions of men, cows, etc. The medicine is, if necessary, mixed with an osmotic pressure- adjusting agent, a pH-adjusting agent, a thickening agent, etc., and subsequently prepared into injections, or mixed with a binder, a lubricant, etc., and subsequently prepared into tablets. The lactoferrin is administered in a concentration of 0.1-10wt.% in the case of the injection or at a daily dose of 1-5,000mg in the case of the oral preparation. The lactoferrin was found to inhibit the degradation of collagen with collagenase and have a new pharmacological activity in addition to a conventional antibacterial activity, a conventional lymphocyte- increasing activity, etc.
Inventors:
Mitsufumi Hikita
Narumi Hayashi
Degres Michel Francois
Narumi Hayashi
Degres Michel Francois
Application Number:
JP164892A
Publication Date:
July 09, 2001
Filing Date:
January 08, 1992
Export Citation:
Assignee:
Biocera Laboratoire
International Classes:
A61K38/16; A61K8/64; A61K38/00; A61K38/40; A61K38/43; A61P29/00; A61P43/00; A61Q11/00; A61Q19/00; (IPC1-7): A61K38/16; A61P29/00
Domestic Patent References:
| JP1135726A | ||||
| JP62501472A |
Attorney, Agent or Firm:
Eisuke Kishimoto (3 others)