Title:
抗血栓性材料
Document Type and Number:
Japanese Patent JP7043936
Kind Code:
B2
Abstract:
To provide an antithrombogenic material that can reduce the amount of adsorption of vWF, a coagulation system protein, to the base material surface while letting it have an anticoagulant activity.SOLUTION: The present invention provides an antithrombogenic material including a nitrogen-containing polymer having an alkylsulfonic acid group, an organic sulfur compound having an anionic anticoagulant activity, and a base material, and in which, when the surface is measured by X-ray photoelectron spectroscopy (XPS), the abundance ratio (N) of nitrogen atoms to the abundance amount of all atoms satisfies the following formula 1. 6.0≤N≤10.0 --- Formula 1 [In the formula, Nrepresents the abundance ratio (number of atoms %) of nitrogen atoms to the abundance amount of all atoms on the surface of the antithrombogenic material.].SELECTED DRAWING: Figure 1
Inventors:
Sou Kakiyama
Koji Kadowaki
Masanori Fujita
Kazuhiro Tanahashi
Koji Kadowaki
Masanori Fujita
Kazuhiro Tanahashi
Application Number:
JP2018069249A
Publication Date:
March 30, 2022
Filing Date:
March 30, 2018
Export Citation:
Assignee:
TORAY INDUSTRIES,INC.
International Classes:
A61L33/06; A61L17/14; A61L27/34; A61L27/40; A61L27/50; A61L29/08; A61L29/12; A61L31/10; A61L31/12; A61L33/10
Domestic Patent References:
| JP2016220717A | ||||
| JP2001190655A |
Foreign References:
| WO2015080177A1 | ||||
| WO2016067795A1 | ||||
| US20100044314 | ||||
| CN102584983A |
Other References:
Langmuir,米国,2016年10月18日,32,p.11763-11770
Chemical Journal of Chinese Universities,2003年05月,24(5),p.916-919
Materials Science and Engineering C,2017年04月02日,77,p.642-648
Chemical Journal of Chinese Universities,2003年05月,24(5),p.916-919
Materials Science and Engineering C,2017年04月02日,77,p.642-648