Title:
抗腫瘍活性2-置換18a-ホモエストラ-1,3,5(10)-トリエン-3-イルスルファメート
Document Type and Number:
Japanese Patent JP2006517947
Kind Code:
A
Abstract:
The invention relates to the use of compounds of a general formula (I), wherein R2, R14 to R17 and X groups have the following significance: R2 is C1-C5-Alkyl, C1-C5-Alkoxy or a -O-CN FmHo rest, wherein n=1,2,3,4,5 or 6, m>1 and m+o=2n+1, R14 and R15 separately designate hydrogen or together a methyl group or a supplementary liaison, R16 is hydrogen; R17 is hydrogen, hydroxy, C1-C5-Alkyl, C1-C5-Alkoxy or SO3NHX; X is hydrogen, C1-C5-alkyl or C1-C5 acyl. In the cycle B and D of a steroid skeleton, stippled lines can additionally represent up to two double bonds. The salts of said compounds which are pharmaceutically acceptable for preparing a drug are also disclosed.
Inventors:
Hirish, alexander
Peters, Olaf
Gege, Christia
Sherlitz-Hoffman, Ina
G-Meister, Gerhard
Unger, Eberhard
Regenhardt, Birco
Peters, Olaf
Gege, Christia
Sherlitz-Hoffman, Ina
G-Meister, Gerhard
Unger, Eberhard
Regenhardt, Birco
Application Number:
JP2006501901A
Publication Date:
August 03, 2006
Filing Date:
February 19, 2004
Export Citation:
Assignee:
Schering Actien Gezel Shaft
International Classes:
C07J41/00; A61K31/565; A61K31/566; A61P5/24; A61P13/00; A61P15/00; A61P35/00; A61P43/00; C07J31/00
Domestic Patent References:
| JP2001527089A | 2001-12-25 | |||
| JP2006517945A | 2006-08-03 | |||
| JP2001507365A | 2001-06-05 | |||
| JPH10507741A | 1998-07-28 |
Foreign References:
| WO2001018028A1 | 2001-03-15 |
Other References:
JPN5006001152, ＭＡＣＣＡＲＴＨＹ−ＭＯＲＲＯＧＨ Ｌ, ＣＡＮＣＥＲ ＲＥＳＥＡＲＣＨ, 20001001, Ｖ６０ Ｎ１９, Ｐ５４４１−５４５０, US, ＡＭＥＲＩＣＡＮ ＡＳＳＯＣＩＡＴＩＯＮ ＦＯＲ ＣＡＮＣＥＲ ＲＥＳＥＡＲＣＨ
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama