PURPOSE: An antitumor agent containing a saponin constituent in the terrestrial part of a medicinal ginseng as an active constituent, and suitable for the oral administration without exhibiting the toxicity and hemolytic action.
CONSTITUTION: An antitumor agent containing a saponin constituent in the terrestrial part of a medicinal ginseng, e.g. panax ginseng C.A. Meyer, Panax japonicus C.A. Meyer or Panax quinquefolium Linne. The saponin constituent consists of ginsenosides expressed by formulasI, II and III [R1 is β-D-glucopyranosyl (1→ 2)-β-D-glucopyranosyl; R2 is β-D-glucopyranosyl(1→6)-β-D-glucopyranosyl, etc.; R3 is α-L-rhamnopyranosyl(1→2)-β-D-glucopyranosyl, etc.; R4 is H or β-D-glucopyranosyl; R5 is β-D-glucopyranosyl; R6 is β-D-glucopyranosyl(1→2)- β-D-glucopyranosyl]. These ginsenosides are obtained by extracting the terrestrial part of the ginseng as a raw material with a solvent, separating and purifying the resultant extract.
YAMAMURA AKIHIRO
CHIYOU KANJIYUN
ITOU RIYUUTA
YAMAMURA AKIHIRO
CHIYOU KANJIYUN
ITO RIYUUTA