Title:
抗腫瘍剤、抗腫瘍剤の製造方法、抗腫瘍剤を含む医薬組成物、及び抗腫瘍剤産生菌
Document Type and Number:
Japanese Patent JP4836783
Kind Code:
B2
Abstract:
It is intended to provide an antitumor agent, which has established a strengthened function selectivity of acting exclusively on caner cells, lessened side effects, mastery of drug tolerance and so on, and has an activity of inducing cell death in human lung small cell carcinoma Ms-1 cells and human lung small cell carcinoma Ms-1/Bcl-2 cells and Ms-1/Bcl-XL cells with the overexpression of an apoptosis-inhibitory protein Bcl-2 or Bcl-XL, and so on. Namely, an antitumor agent characterized by being a compound represented by the following general formula or its derivative. [Chemical formula 12] wherein R represents a hydrogen atom or an alkyl group.
Inventors:
Yoshikazu Takahashi
Ryuichi Sawa
Masaya Imoto
Nimura Yuji
Ryuichi Sawa
Masaya Imoto
Nimura Yuji
Application Number:
JP2006513728A
Publication Date:
December 14, 2011
Filing Date:
May 19, 2005
Export Citation:
Assignee:
Institute for Microbial Chemistry
International Classes:
A61K31/7052; A61K35/74; A61P35/00; C07H17/02; C12N1/20; C12P17/16; C12R1/465
Other References:
Thawai, C. et al.,Chemistry & Biodiversity,2004年,Vol.1(4),pp.640-645
Attorney, Agent or Firm:
Koichi Hirota
Yoshihiro Nagare
Naoko Matsuda
Yoshihiro Nagare
Naoko Matsuda