Title:
抗腫瘍テストステロン-(放射性ヨウ素)化合物
Document Type and Number:
Japanese Patent JP2014515025
Kind Code:
A
Abstract:
The present invention can be used as an antitumour drug for testosterone-dependent tumours, in particular prostate cancer. The invention relates to a molecular compound composed of testosterone molecules chemically bonded to a chemotherapeutic radioactive iodine atom (I-124, 125 or 131) aimed at combating testosterone-dependent tumours, in particular prostate cancer, eliminating the undesirable collateral effect of known chemotherapeutic compounds, which is the destruction of rapid growth cells such as white blood cells. The main contribution of the invention is the use of testosterone as the chemotherapeutic agent carrier. In particular, a testosterone molecule chemically bonded to a radioactive iodine atom is used, which can be iodine-125, 125 or 131.
Inventors:
Silva Paiva, Gerson
Desosa, Yvoni Antonia
Taft, Carlton Anthony
Desosa, Yvoni Antonia
Taft, Carlton Anthony
Application Number:
JP2014505466A
Publication Date:
June 26, 2014
Filing Date:
April 17, 2012
Export Citation:
Assignee:
UNIVERSIDADE FEDERAL DE PERNAMBUCO
CENTRO BRASILEIRO DE PESQUISAS FISICAS - CBPF
CENTRO BRASILEIRO DE PESQUISAS FISICAS - CBPF
International Classes:
C07J1/00; A61K31/568; A61P35/00
Attorney, Agent or Firm:
sk patent corporation
Akihiko Okuno
Hiroyuki Ito
Akihiko Okuno
Hiroyuki Ito