Title:
APPLICATION OF EPIGENETIC CHROMOSOMAL INTERACTIONS IN CANCER DIAGNOSTICS
Document Type and Number:
Japanese Patent JP2023027076
Kind Code:
A
Abstract:
To provide methods of determining the epigenetic chromosome interactions which are relevant to a prognostic companion epigenetic test for cancer.SOLUTION: Disclosed is a method comprising: contacting a first set of nucleic acids from a subgroup with a second set of nucleic acids representing a chromosomal interaction index population; and hybridizing complementary sequences, the nucleic acids in the first and second sets of nucleic acids together representing a ligation product that includes sequences from both chromosomal regions that interact epigenetically, and the pattern of hybridization between the first and second sets of nucleic acids making the determination of which epigenetic chromosome interactions are specific to a subgroup in the population.SELECTED DRAWING: Figure 1
Inventors:
Grand, Francis Hector
Ramadas, Alaul Selvam
Akourichev, Alexandre
Hunter, yuan
Ramadas, Alaul Selvam
Akourichev, Alexandre
Hunter, yuan
Application Number:
JP2022183117A
Publication Date:
March 01, 2023
Filing Date:
November 16, 2022
Export Citation:
Assignee:
Oxford BioDynamics PLC
International Classes:
C12Q1/6886; C12Q1/6851; C12Q1/686
Attorney, Agent or Firm:
Kita Aoyama International Patent Attorney Corporation