To obtain an aqueous injection containing miconazole, which does not requires preparation such as dilution in use, has no fear of bacterial infection and foreign material mixing in a medical site, improved user-friendliness, excellent long-term storage stability, is made isotonic and contains miconazole or its pharmaceutically permissible salt.
The miconazole-containing aqueous injection having long-term storage stability contains ≤1.0 mass % based on the whole amount of the preparation, ≤10 mass % of a solubilizer, a pH adjuster and an isotonizing agent, is made isotonic and is packed into a sealed container. The remaining oxygen amount in the sealed container is adjusted to ≤1.5 mL based on 200 mg miconazole and the solution has pH 4.2-5.2.
JP4463317 | Substituted imidazole and its use as an insecticide |
JPS6185367 | 4,5-DIHYDRO-3(2H)- |
WO/2002/100813 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS |
Haruko Sanwa
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