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Title:
アルギナーゼ阻害剤およびそれらの治療用途
Document Type and Number:
Japanese Patent JP5898177
Kind Code:
B2
Abstract:
where R1, R2, R3, R4, R5, R6, R7, R8, R9, D, M, X, and Y are defined as set forth in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use for treating or preventing a disease or a condition associated with arginase activity.

Inventors:
Banzant Michael
Goenbio Offsky Adam
Jiminck
White House Darren
Rider todd
Becket pole
Application Number:
JP2013506268A
Publication Date:
April 06, 2016
Filing Date:
April 20, 2011
Export Citation:
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Assignee:
MARS INCORPORATED
International Classes:
C07F5/02; A61K31/69; A61P1/00; A61P1/02; A61P1/04; A61P1/14; A61P1/16; A61P3/10; A61P7/00; A61P7/06; A61P9/00; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P13/02; A61P13/12; A61P15/10; A61P17/00; A61P17/02; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/00; A61P25/08; A61P25/28; A61P29/00; A61P31/04; A61P31/10; A61P31/18; A61P31/20; A61P33/02; A61P35/00; A61P37/02; A61P37/06; A61P43/00
Domestic Patent References:
JP2012515799A
Foreign References:
WO1999019295A1
WO2007005620A1
Other References:
Bioorganic & Medicinal Chemistry,2005年,Vol.13,p.2373-2379
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto