Title:
ARYLSULFOXIDE ENZYME INHIBITOR
Document Type and Number:
Japanese Patent JPS5630960
Kind Code:
A
Abstract:
Organic sulfoxides of formula having a latent allyl group bound to the sulfur, are enzyme inhibitors of the suicide or Kcat type. They can be prepared by oxidation of the corresponding thio compounds followed by deesterification. Their pharmaceutical compositions are also a part of the invention.
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Inventors:
REIMONDO EE FUAIASUTOON
Application Number:
JP11186480A
Publication Date:
March 28, 1981
Filing Date:
August 15, 1980
Export Citation:
Assignee:
MERCK & CO INC
International Classes:
A61K31/13; A61K31/135; A61K31/19; A61K31/195; A61K31/22; A61K31/33; A61K31/397; A61K31/10; A61K31/40; A61K31/403; A61K31/404; A61K31/41; A61K31/545; A61K31/546; A61P9/12; A61P31/04; A61P35/00; A61P43/00; C07C67/00; C07C313/00; C07C315/02; C07C317/00; C07C317/18; C07C317/44; C07C317/48; C07C319/20; C07C323/59; C07C323/65; C07D209/20; C07D233/54; C07D233/64; C07D233/84; C07D239/38; C07D241/18; C07D333/18; C07D463/00; C07D477/00; C07D487/04; C07D501/00; C07D501/24; C07D521/00; C07F9/09; C07F9/40; (IPC1-7): A61K31/10; A61K31/13; A61K31/19; C07C147/14; C07C149/44; C07F9/08
Domestic Patent References:
| JPS5481219A | 1979-06-28 | |||
| JP45020486A |