Title:
トロンビン基質およびサンプル中の生体活性トロンビンのレベルを測定するためのアッセイ
Document Type and Number:
Japanese Patent JP5606435
Kind Code:
B2
Abstract:
Substrates for thrombin and assays for determining the level of bioactive thrombin in a sample are disclosed, wherein the substrate has the general formula: A-X-Z-A' wherein one of either A or A' comprises a luminescent chelate and the other one of A or A' comprises a first partner of a binding pair, X forms a tri- or tetra-peptide, and Z comprises a linker.
Inventors:
Ching and Chiu * pin
タカロ, Harry
Bernard, Alan Milton
Jacobsen, Kirstein Marie
タカロ, Harry
Bernard, Alan Milton
Jacobsen, Kirstein Marie
Application Number:
JP2011517751A
Publication Date:
October 15, 2014
Filing Date:
July 10, 2009
Export Citation:
Assignee:
Radio meter medical アー pay S
International Classes:
C12Q1/37; C12Q1/56; G01N33/86; C07K5/087; C07K5/11
Attorney, Agent or Firm:
Ono Shinjiro
Kobayashi 泰
Shigeo Takeuchi
Yamamoto 修
Shinobu Hirose
Kobayashi 泰
Shigeo Takeuchi
Yamamoto 修
Shinobu Hirose