Title:
PPARリガンドと抗酸化剤の会合および肥満の治療のためのその使用
Document Type and Number:
Japanese Patent JP2006505548
Kind Code:
A
Abstract:
Combinations of at least one peroxisome proliferator activated receptor (PPAR) ligand (I) and an antioxidant (II). ACTIVITY : Anorectic; Antioxidant. In tests in C57 Black 6 ob/ob male rats, the change in body weight after intraperitoneal injection once daily with test compound(s) for 14 days was approximately +10% for rosiglitazone (Ia) alone and approximately -50% for a combination of (Ia) and coenzyme Q 1 0 (no dosages given). MECHANISM OF ACTION : PPAR receptor ligand (agonist).
Inventors:
Castile, Louis
Peniko, Luc
Dakke, Catherine
Renard, Pierre
Peniko, Luc
Dakke, Catherine
Renard, Pierre
Application Number:
JP2004542579A
Publication Date:
February 16, 2006
Filing Date:
October 10, 2003
Export Citation:
Assignee:
Réra Bora Toir Servier
International Classes:
A61K31/4439; A61K31/122; A61K45/06; A61P3/04; A61P3/08; A61P3/10; A61P5/48; A61P5/50; A61P43/00; C07D417/12
Foreign References:
| WO2002034259A1 | 2002-05-02 | |||
| WO2002064549A1 | 2002-08-22 |
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda