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Title:
自動化可能なユニバーサル試料調製方法
Document Type and Number:
Japanese Patent JP4048022
Kind Code:
B2
Abstract:
Isolation of an analyte (I) from a biological sample comprising: (i) decomposing the sample in a reaction vessel; (ii) adding a solid adsorption matrix (A); (iii) incubating so that (I) binds to (A); (iv) removing non-bound components from the vessel; (v) incubating so that (I) is eluted from (A); and (vi) separating the eluate from (A). Independent claims are also included for the following: (1) reagent kits for the process comprising protease; buffers for sample decomposition, washing and elution, and a suspension of magnetic glass particles; (2) apparatus for the process; and (3) magnetic glass particles (B) comprising a magnetic core and glass shell containing silica, boron oxide and alkali metal oxide, optionally also alumina and alkaline earth metal oxide.

Inventors:
Klaiber, Jörg
Markert-Hahn, Christine
Hultteak, Herbert
Application Number:
JP2000513863A
Publication Date:
February 13, 2008
Filing Date:
September 29, 1998
Export Citation:
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Assignee:
Roche Diagnostics Gaem Behr
International Classes:
C12N15/09; G01N33/50; B01D43/00; B03C1/00; B03C1/01; C03C14/00; C12M1/00; C12N15/10; C12Q1/68; C12Q1/6806; G01N1/28; H01F1/11; G01N35/00
Domestic Patent References:
JP2289596A
JP11509364A
JP5507613A
Attorney, Agent or Firm:
Yoshinori Hosoda