生体液からの細胞外小胞の単離及びセルフリーＤＮＡの同時単離のための自動及び手動方法

Japanese Patent JP7037504

B2

The invention provides novel methods and kits for fully automated high-throughput method for isolation of extracellular vesicles and co-isolation of cell-free DNA from biofluids, including cell-free DNA and/or cell-free DNA and nucleic acids including at least RNA from microvesicles, novel methods and kits for isolation of extracellular vesicles and co-isolation of cell-free DNA from biofluids, including cell-free DNA and/or cell-free DNA and nucleic acids including at least RNA from micro vesicles that do not require the use of phenol or chloroform, and for extracting nucleic acids from the extracellular vesicles and/or from the biological samples.

WO/1985/003951	REAGENTS AND KITS FOR THE QUANTITATIVE DOSING OF A VIRAL NUCLEIC ACID IN A BIOLOGICAL MEDIUM AND METHOD FOR DOSING SAID VIRAL NUCLEIC ACID
WO/1993/025903	TEST FOR PERIODONTITIS AND SUSCEPTIBILITY THERETO
JP2004502781	Methods for Preventing Nervous Tissue Damage and Treating Alpha-synuclein Disease

Georg Stall
Daniel Endale
Mickel Noah Holm
Joan Karl Olab Skog

JP2018559313A

March 16, 2022

May 15, 2017

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Exo Sam Diagnostics, Incorporated

G01N33/50; C12N5/07; C12N15/10; C12P19/34; C12Q1/6806

JP2008510456A
JP2016502862A

WO2016007755A1
US20160115471
US20150010951

ENDERLE D; ET AL,DEVELOPMENT OF A ONE-STEP ISOLATION PLATFORM FOR EXOSOMAL RNA AND CIRCULATING CELL-FREE DNA FROM CANCER PLASMA SAMPLES,EUROPEAN JOURNAL OF CANCER - POSTER SESSION,2014年11月,VOL:50, NR:SUPPL.6,PAGE(S):102,http://dx.doi.org/10.1016/S0959-8049(14)70439-3

Aoki Atsushi
Shinji Mihashi
Youichi Watanabe
Nakajima Masaru
Ryotaro Takei
Kumi Kitamura

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