Title:
AVERMECTIN BIOLOGICALLY CONVERTED PRODUCT
Document Type and Number:
Japanese Patent JPS61233686
Kind Code:
A
Abstract:
There are disclosed novel compounds which are derived from 22,23-dihydro avermectin B1a aglycone and 13-deoxy-22,23-dihydro avermectin B1a and B1b aglycones. The compounds are hydroxy adducts of the substrate avermectin compound at one or two of the 12a, 13-epi. 14a, 24, 24a, 26, 26a and 27 positions. They are prepared by incubating the substrate with the microorganism Cunninghamella blakesleeana (ATCC 8688a) and isolating the hydroxy adducts from the fermentation broth. The compounds are highly potent antiparasitic, insecticidal and anthelmintic agents.
Inventors:
ROBAATO TEE JIYOOJIRUMAN
REIMONDO EFU HOWAITO
EDOWAADO ESU INAMINE
REIMONDO EFU HOWAITO
EDOWAADO ESU INAMINE
Application Number:
JP4548886A
Publication Date:
October 17, 1986
Filing Date:
March 04, 1986
Export Citation:
Assignee:
MERCK & CO INC
International Classes:
C07D493/22; A01N43/90; A23K1/16; A61K31/365; A61P33/10; C07H19/01; C12P17/08; C12P17/18; C12P19/44; C12R1/645; (IPC1-7): A01N43/90; A23K1/16; A61K31/365; C07D307/00; C07D311/00; C07D313/00; C07D493/22; C12P17/18; C12R1/645
Attorney, Agent or Firm:
Masao Okabe
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