Title:
Aza-indole derivatives
Document Type and Number:
Japanese Patent JP5938533
Kind Code:
B2
Abstract:
Provided is a novel compound having a selective JAK3-inhibitory effect and also having excellent oral absorbability. Also provided is a pharmaceutical agent, which is based on a JAK3-inhibitory effect and is useful for preventing and/or treating a disease involving the JAK3, and in particular, rheumatoid arthritis or multiple sclerosis. An azaindole derivative having a cycloalkenyl group, which is represented by the following formula (I), or a salt thereof, and a pharmaceutical composition containing the same:
where R 1 to R 4 , m and n have the same meanings as those defined in the description.
Inventors:
Masayuki Nakamura
Hiroyoshi Yamanaka
Kazuro Shibata
Mitsuhiro Mitsuya
Takashi Harada
Hiroyoshi Yamanaka
Kazuro Shibata
Mitsuhiro Mitsuya
Takashi Harada
Application Number:
JP2015560995A
Publication Date:
June 22, 2016
Filing Date:
February 04, 2015
Export Citation:
Assignee:
Taiho Pharmaceutical Co., Ltd.
International Classes:
C07D471/04; A61K31/437; A61K31/444; A61K31/5377; A61P1/04; A61P3/10; A61P11/00; A61P11/02; A61P11/06; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P21/00; A61P25/00; A61P25/28; A61P27/14; A61P27/16; A61P29/00; A61P31/12; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P37/08; A61P43/00
Domestic Patent References:
| JP2008545660A | 2008-12-18 | |||
| JP2008513352A | 2008-05-01 | |||
| JP2007504252A | 2007-03-01 | |||
| JP2010517980A | 2010-05-27 | |||
| JP2008545660A | 2008-12-18 | |||
| JP2008513352A | 2008-05-01 | |||
| JP2007504252A | 2007-03-01 | |||
| JP2010517980A | 2010-05-27 |
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto